Founder & CEO - Oncology Biotech Job at CSG Talent, Cambridge, MA

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  • CSG Talent
  • Cambridge, MA

Job Description

Founder & CEO - Oncology Biotech (ADC/Cancer Stem Cell Therapy)
Location: U.S. or Europe | Type: Co-founder Opportunity

A preclinical biotech venture is seeking a Founder & CEO to lead development of a first-in-class protein drug conjugate (PDC) targeting cancer stem cells (CSCs)-a critical driver of metastasis, recurrence, and drug resistance.

The technology, based on natural ligands of LGR4/5/6 receptors, has shown strong anti-tumor activity in preclinical models of colorectal, ovarian, and gastric cancer. Backed by a prominent research foundation and supported by an experienced inventor, the company is poised for IND-enabling studies and first-in-human trials.

Responsibilities:

  • Drive both dilutive and non-dilutive fundraising

  • Shape clinical and regulatory strategy

  • Oversee preclinical and IND-enabling activities

  • Build partnerships with CROs, CDMOs, pharma, and KOLs

  • Lead the company through early clinical development

Ideal Profile:

  • Proven experience in biotech fundraising and leadership

  • Background in ADC or biologics development

  • Strong oncology network and scientific credibility

  • Familiarity with early-stage clinical and regulatory milestones

The Opportunity:

  • Equity-based co-founder role

  • Compensation tied to successful fundraising

  • Access to infrastructure and support from a broader venture-building ecosystem

This is a rare opportunity to lead a scientifically differentiated oncology company from inception through early clinical development.

Desired Skills and Experience

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